Rapid growth of Merkel cell carcinoma after treatment with rituximab
Wirges, M.L.; Saporito, F.; Smith, J.
Journal of Drugs in Dermatology Jdd 5(2): 180-181
2006
ISSN/ISBN: 1545-9616 PMID: 16485888 Document Number: 9751
Merkel cell carcinoma is an uncommon neuroendocrine carcinoma of the skin. We report a case of rapid growth of Merkel cell carcinoma after treatment with rituximab, a new anti-CD20 monoclonal antibody, for acquired factor VIII inhibitor. We propose that rituximab may place patients at higher risk for aggressive Merkel cell carcinoma thus necessitating the need for increased long-term surveillance of these patients.
Document emailed within 1 workday
