Peculiarities of cardiac activity in renal form of experimental hypertension with different hemodynamic characteristics
Stroganova, N.P.
Kardiologiia 15(8): 48-53
1975
ISSN/ISBN: 0022-9040 PMID: 1195549 Document Number: 94287
The main haemodynamic indices were studied in rabbits of two age groups (young -- 10--12 month, and old -- 3--4 years) under normal conditions and those with experimentally induced renal hypertension. Significant changes were observed in the proportion of the main parameters of haemodynamics -- cardiac output per 1 min and total peripheral resistance -- in the presence of persistent arterial hypertension, which permitted to single out three haemodynamic forms of experimentally induced renal hypertension. The first and second haemodynamic forms are characterized by a sharp enhancement of the total peripheral resistance and diverse changes in the values of cardiac output per 1 min.: the third haemodynamic form is predmoninatly characterized by an elevation of the cardiac output. The compensatory hyper-function of the myocardium in the first and second forms of renal hypertension develops usually isometrically, in the third form -- according to the mixed variant.