Serological analysis of an oncornavirus (PMF virus) detected in malignant permanent human cell lines

Micheel, B.; Papsdorf, G.; Wunderlich, V.; Niezabitowski, A.; Widmaier, R.; Bender, E.; Graffi, A.

Acta Biologica et Medica Germanica 34(4): K39-K45

1975


ISSN/ISBN: 0001-5318
PMID: 171892
Document Number: 93414
Immunodiffusion analysis of the PMF virus which was detected in malignant permanent human cell lines revealed positive reactions with antisera against the Mason-Pfizer monkey virus (MPMV). No cross-reactivity was demonstrated with murine leukemia virus (MuLV), rat leukemia virus (RaLV), hamster leukemia virus (HaLV), feline leukemia virus (FeLV), simian (woolly monkey) sarcoma virus (SSV-1) and mouse mammary tumor virus (MTV). The cross-reactive antigens of the PMF virus and the MPMV are considered as evidence for the human origin of the PMF virus.

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