Efficacy of lincomycin and spectinomycin on canine pathogens
Hamdy, A.H.
Laboratory Animal Science 25(5): 570-574
1975
ISSN/ISBN: 0023-6764 PMID: 127073 Document Number: 91595
Lincomycin (L), spectinomycin (S), and both (L-S) were evaluated in vitro and in vivo against canine pathogens (Mycoplasma sp., Staphylococcus aureus, beta-hemostreptococcus and Pasteurella multocida. In vitro, a wider spectrum of antimicrobial activity was achieved with L-S than with either L or S. The therapeutic effects of the antibiotics were investigated in 36 dogs inoculated with a mixture of the microbal agents. Tonsillitis, conjunctivitis, laryngitis, abscess formation, and necropsy findings were measured. The L-S combination was effective for the treatment of tonsillitis, conjunctivitis, laryngitis, and pneumonia in dogs.