Variations in sensitivity of synchronized Chinese hamster cells to oxic and anoxic X-ray exposures
Siracká, E.; Littbrand, B.; Clifton, K.H.; Révśz, L.
Neoplasma 22(6): 647-653
1975
ISSN/ISBN: 0028-2685 PMID: 1214926 Document Number: 85274
V-79 Chinese hamster cells in monolayer cultures on glass surfaces were synchronized by treatment with hydroxyurea and exposed at different times to X-rays in air or in O2-free Ar. Survival determinations indicated that the O2 enhancement ratio [OER] as expressed by the ratio of the respective D0 values varied over a narrow range in the different phases of the cell cycle. These changes resulted from cyclic alterations in both aerobic and anaerobic D0 values and perhaps in n values.