Immunization against Q-fever of naturally infected dairy cows
Sádecký, E.; Brezina, R.; Kazár, J.; Urvölgyi, J.
Acta Virologica 19(6): 486-488
1975
ISSN/ISBN: 0001-723X PMID: 1994 Document Number: 84535
Cows infected naturally with Coxiella burnetii as evidenced either by presence of phase II agglutinating antibodies in the blood or by shedding C. burnetii in the milk were vaccinated s/c with formalin-killed phase I C. burnetii organisms. Attempts to demonstrate C. burnetii in the milk 47 days after vaccination were negative, while continuous shedding of C. burnetii in the milk of control, unvaccinated cows was repeatedly demonstrated in the course of 123 days (period of investigation). No harmful systemic reaction following vaccination was observed.