Effect of immunization of mice with live viral vaccines on bone marrow cell chromosomes in 1st generation progeny

Gorshunova, L.P.; Mikhaĭlova, G.R.; Cherkeziia, S.E.

Tsitologiia i Genetika 9(6): 542-545

1975


ISSN/ISBN: 0564-3783
PMID: 1221580
Document Number: 83655
In bone marrow cells of the first generation progeny obtained from mice intensively immunized with live antiviral vaccines (poliovaccine, measles and smallpox vaccines) an increase of chromosome frequency aberrations is observed mainly due to chromatid breaks. Simultaneously a considerable delay in growth was determined for progeny obtained from the vaccinated animals as compared with the control.

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