Acquired isolated factor VII deficiency and bronchogenic carcinoma. A case report

Zili, M.; Hammami, S.; Marghli, A.; Mechmech, L.; Boughnim, L.; Abid, S.; Brahim, N'siri.; Toumi, N.El.Houda.; Kilani, T.; Yaalaoui, S.

La Tunisie Medicale 83(6): 363-365

2005


ISSN/ISBN: 0041-4131
PMID: 16156413
Document Number: 8195
An acquired factor VII deficiency was identified in a 63-year-old man with bronchogenic carcinoma. Initial studies indicated a normal activated partial thromboplastin time and a prolonged prothrombin time. The factor VII level was 6%. No evidence of a factor VII inhibitor or inactivator was demonstrable. However, on account of the initial normal laboratory test of emostases, the partial correction of the prothrombin time with 50% normal plasma in vitro and the family history, the congenital deficiency in factor VII was ruled out. Whatever the mechanism involved, this factor VII deficiency was related to malignancy.

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Acquired isolated factor VII deficiency and bronchogenic carcinoma. A case report