Acquired Factor VII Deficiency in Association with Pyelonephritis
Anand, M.; Babbar, N.
Journal of the Association of Physicians of India 66(5): 95-96
2018
ISSN/ISBN: 0004-5772 PMID: 30477072 Document Number: 696486
Acquired factor VII (FVII) deficiency in the absence of vitamin K deficiency, oral, synthetic liver dysfunction, or DIC is rare, with only a handful of cases published in literature. Congenital deficiency of FVII is well known but, little is known about secondary FVII deficiency and its management. The knowledge of this syndrome should avoid false diagnosis of congenital factor VII deficiency. Here, we present the report of a young woman who presented with pyelonephritis, anaemia, prolonged prothrombin time and normal activated partial prothrombin time (aPTT). She was diagnosed to have acquired FVII deficiency and this was the first such case with pyelonephritis.