Facilitation of avoidance conditioning by nicotine: a function of individual learning ability
Székely, J.I.; Borsy, J.; Király, I.
Acta Physiologica Academiae Scientiarum Hungaricae 45(3-4): 293-295
1974
ISSN/ISBN: 0001-6756 PMID: 4471274 Document Number: 80072
A conditioned avoidance response was elaborated in automatic shuttle boxes in rats and the effect of post-trial nicotine treatment on learning performance was measured. The animals were individually qualified as poor or good learners according to their 1st day, i.e., pretreatment performance. Nicotine in a dose of 0.05 mg/kg had no significant effect, while in doses of 0.10-0.20 mg/kg it facilitated the acquisition of the conditioned response only in the group of good learners.