Ability of cipramil to correct conditioned passive avoidance in ovariectomized female rats
Fedotova, I.O.; Sapronov, N.S.
Eksperimental'naia i Klinicheskaia Farmakologiia 66(1): 8-11
2003
ISSN/ISBN: 0869-2092 PMID: 12683072 Document Number: 555497
The ability of cypramil, a selective inhibitor of serotonin re-uptake, to modify the cognitive performance was studied in ovariectomized female rats with passive avoidance paradigm and in the open-field test. It was found that cypramil in combination with estradiol restored the formation and retention of the passive avoidance performance. In addition, cypramil improved the emotional component of behavior in the open-field test.