Comparative analysis of conditioned passive avoidance retention in rats with different forms of inherited arterial hypertension
Loskutova, L.V.; Dubrovina, N.I.; Markel', A.L.
Rossiiskii Fiziologicheskii Zhurnal Imeni I.M. Sechenova 92(4): 440-448
2006
ISSN/ISBN: 0869-8139 PMID: 16813150 Document Number: 603226
Comparing behavioral traits of anxiety in elevated plus-maze and retention of passive avoidance response in two rat strains with hereditary arterial hypertension ISIAH (inherited stress induced arterial hypertension) and SHR (spontaneously hypertensive rats) has shown the following. The SHR rats demonstrate impairment in retrieval of passive avoidance, hyperactivity and low anxiety. ISIAH rats showned better avoidance performance, average level of anxiety and activity. The interdependence of two pathologies: hypertension and memory impairment is discussed.