Behavior of phagocytosis in experimental Trichomonas vaginalis infection in mice
Poli, G.; Cappuccinelli, P.; Sena, L.; Longhin, P.P.
Bollettino della Societa Italiana di Biologia Sperimentale 50(20): 1680-1683
1974
ISSN/ISBN: 0037-8771 PMID: 4549427 Document Number: 79115
When T. vaginalis is injected s.c. into mice, an abscess forms similar to that induced by pyogenic bacteria. Under these conditions, phagocytosis reaches levels 4 times greater than controls. When T. vaginalis is administered intravaginally, there is only a slight, brief increase in phagocytic activity of polymorphonuclear leukocytes. In intravaginal infection the parasite remains localized almost exclusively in the lumen, with little involvement of surrounding tissues.