The characteristics of the neuropsychotropic activity of bromantane in laboratory animals
Morozov, I.S.; Klimova, N.V.; Karpova, T.D.; Shestopalov, S.S.
Eksperimental'naia i Klinicheskaia Farmakologiia 62(2): 3-6
1999
ISSN/ISBN: 0869-2092 PMID: 10340117 Document Number: 7751
Bromantan [N-2-(para-(bromphenyl)-N-2-(aminoadamantan)] possesses psychostimulating activity in experiments on animals. With LD50 8100 mg/kg (mice, intraperitoneal injection) activates simple and complicated forms of behavior, induces EEG effects typical of psychostimulators, is an antagonist of substances with a deprivationg neuropsychotropic effect. Bromantan is characterized by a positive effect on mnemonic processes and on obtaining the results of complex operant activity in rats.
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