Bidirectional modification of hypothalamic self-stimulation by noradrenaline in the cat
Angyán, L.; Darbinjan, A.; Solymosi, L.
Acta Physiologica Academiae Scientiarum Hungaricae 45(1-2): 139-143
1974
ISSN/ISBN: 0001-6756 PMID: 4470849 Document Number: 76218
Noradrenaline injected i.m. into 4 cats exerts opposite effects on self-stimulation behavior, depending on the dosage. A small dose of noradrenaline greatly facilitated the lever-pressing behavior, while a large dose of the drug depressed it. The changes induced in the arterial blood pressure were an excellent indicator of the reversal in the effect of noradrenaline on self-stimulation behavior.