Pathogenic properties of six bovine picornavirus isolates in mice
Mattson, J.M.; Vorhies, M.W.; Reed, D.E.
American Journal of Veterinary Research 35(12): 1545-1548
1974
ISSN/ISBN: 0002-9645 PMID: 4372915 Document Number: 75101
Six bovine picornavirus isolates were classified according to mouse pathogenicity. Of the 6 isolates, 4 (6727 sm, 4155 sm, 3039, and 7109) produced lesions, and 3 (6727 sm, 4155 sm, and 3039) produced death in suckling mice. Microscopic lesions included necrosis in brain, heart, lung, liver, and kidney. A correlation between mouse pathogenicity and haemagglutination was found, indicating that haemagglutination properties may be helpful in classifying picornaviruses.