Pharmacological studies on anethole trithione
Ukai, Y.; Shiraishi, M.; Takeshita, K.; Fukui, T.; Kura, K.; Kimura, K.
Arzneimittel-Forschung 38(10): 1460-1465
1988
ISSN/ISBN: 0004-4172 PMID: 3196385 Document Number: 720
Pharmacological studies on trithio-p-methoxy-phenylpropene (anethole trithione, ANTT, Felviten) were performed. ANTT at a dose of 100 mg/kg, p.o. lowered the increased serum transaminases GOT and GPT, and protected the liver from injuries caused by CCl4 in mice. In other studies in vivo, ANTT at a dose of 1000 mg/kg showed no effect on the central nervous system or the autonomic nervous system. In vitro experiments with smooth muscle preparations showed no significant effects of ANTT.
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