Erythroderma with circulating atypical T-cells, likely Sézary syndrome
Ugonabo, N.; Kim, R.; Chen, L.; Meehan, S.; Weed, J.
Dermatology Online Journal 25(12)
2019
ISSN/ISBN: 1087-2108 PMID: 32045168 Document Number: 699418
The erythrodermic patient is often challenging and requires careful evaluation. Work-up should include an extensive and careful medication history, histological and laboratory testing, and if necessary, molecular studies for the evaluation of underlying malignancy. Herein, we present an erythrodermic patient with repeated biopsies demonstrating a spongiotic process who was found to have circulating atypical T-cells concerning for an underlying erythrodermic T-cell leukemia, most closely related to Sézary syndrome.