Sezary syndrome with arthropathy. Report of a case
Furey, N.L.; Furey, W.W.; Yonan, T.N.; Esterly, N.B.
Acta Dermato-Venereologica 55(5): 381-386
1975
ISSN/ISBN: 0001-5555 PMID: 52975 Document Number: 93954
A 65-year-old black female with Sezary syndrome had generalized intractable pruritus, erythroderma, alopecia, onychogryphosis, lumphadenopathy and hepatomegaly. Abnormal lymphocytes with large, convoluted and grooved nuclei (Sezary cells) were identified in the skin and peripheral blood. A striking feature of her disease was severe, deforming arthropathy of the hands and knees, a clinical finding which has been described previously in only one patient with Sezary syndrome. At necropsy no associated lymphoma was found.