Progress in research of influence of gene polymorphisms on immune response
Cao, J.Q.; Li, J.X.; Wang, Y.Y.; Zhu, F.C.
Zhonghua Liu Xing Bing Xue Za Zhi 39(11): 1515-1518
2018
ISSN/ISBN: 0254-6450 PMID: 30462964 Document Number: 695254
基因在免疫系统应答过程中扮演着重要的角色，不同的基因位点可能引起疫苗免疫应答率的高低差异。本文对基因多态性与疫苗免疫应答的文献进行综述，旨在探究基因多态性会对疫苗免疫应答产生的影响，从基因水平上探讨个体接种疫苗后产生免疫应答的效果，为个体化免疫发展策略提供科学依据。综述结果显示人类白细胞抗原基因、各类细胞因子及其受体基因、Toll样受体类基因的单核苷酸多态性都会影响疫苗免疫应答。.
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