Antibiotics Resistance of Corynebacterium non Diphtheriae Strains
Kharseeva, G.G.; Voronina, N.A.; Gasretova, T.D.; Sylka, O.I.; Tyukdvkina, S.Y.
Zhurnal Mikrobiologii Epidemiologii i Immunobiologii 2: 3-8
2017
ISSN/ISBN: 0372-9311 PMID: 30695529 Document Number: 694510
Study the frequency of occurrence of antibiotics resistant strains of various species of Corynebacterium non diptheriae. C.pseudodiphtheriticum, C.pseudo- tuberculosis, C.xerosis, C.amycolatum, C.striatum, C. ulcerans strains isolated from patients with pathologies of respiratory and urogenital tract, as well as individuals taking prophylaxis ex- amination were used. Sensitivity to antibacterial preparations was determined by the serial dilution method. The highest number of Coryniebacterium non diptheriae strains dis- played resistance to benzylpenicillin (54.8%) and lincomycin (50.7%), and lowest - to cefotaxime, cefazolin (6.8%) and vancomycin (13.7%). The highest number of antibiotics resistant strains were detected among members of C.pseudotuberculosis (100%), C.xerosis (96.0%) and C. pseudodiphtheriticum (81.0%) species. Polyresistant strains were detected most frequently among C.xerosis, C.amycolatum and C.striatum species. Strains of Corynebacterium non diptheriae most frequently displayed resistance to 1 or 2 antibacterial preparations (24.7%), less frequently - to 3 (20.5%); 4 (13.7%), 5 (4.1%) and 6 (1.4%) preparations. The amount of antibiotics resistant strains of Cdrynebacterium non diptheriae is large (89.0%) and non-similar in various species.