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Immunomodulating properties of the antigens of the cell walls of nontoxigenic Corynebacterium diphtheriae

Shmeleva, E.A.; Kondrashina, N.N.; Baturina, I.G.

Antibiotiki i Khimioterapiia 33(8): 601-605

1988

ISSN/ISBN: 0235-2990
PMID: 3143322
Document Number: 316599
The total protein fraction was obtained by extraction with nonionic detergent NP-40. The fraction composition and molecular parameters were studied with DDS-Na electrophoresis in polyacryl amide gel. Common properties of the Corynebacterium diphtheriae protein fraction 66 kD and an analogous fraction of the cell walls of staphylococci and the measles virus were shown with immunoblotting. Cell-mediated mechanisms of the immune response to contact with antigens of Corynebacterium diphtheriae cell walls were revealed.

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