Effect of methoxylated flavones on erythrocyte aggregation and sedimentation in blood of normal subjects: evidence of a dietary role for flavonoids
Robbins, R.C.
International Journal for Vitamin and Nutrition Research. Internationale Zeitschrift für Vitamin- und Ernahrungsforschung. Journal International de Vitaminologie et de Nutrition 43(4): 494-503
1973
ISSN/ISBN: 0300-9831 PMID: 4769343 Document Number: 69435
The antiadhesive activity of 3 flavonoids from citrus fruit was estimated from the erythrocyte sedimentation rate (ESR) of 48 healthy subjects. ESR was reduced 78.8% by pentamethoxyflavone (sinensetin), 70.8% by hexamethoxyflavone (nobiletin) and 63.9% by heptamethoxyflavone when they were added to blood at a concentration of 48 mu M or 17.9, 19.3 and 20.8 mu g/ml, respectively.