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Effects of acute loading of alcohol on platelet aggregation in normal subjects

Galante, A.; Lenci, R.; Pierangeli, L.; Filice, A.; Calcagnini, G.; Chessa, C.

La Clinica Terapeutica 128(4): 267-270

1989

ISSN/ISBN: 0009-9074
PMID: 2524316
Document Number: 335929
Ten healthy subjects were submitted to alcohol loading (0.8 g/kg body weight; average alcohol blood level 0.97 g 0/00). The number of platelets, hematocrit and ADP-induced platelet aggregation curves did not show any variation from baseline. Significant changes (p less than 0.05) were observed as regards latent period (increased) and maximum amplitude (reduced) for collagen-induced platelet aggregation. In agreement with others, the authors conclude that alcohol definitely inhibits platelet aggregation.

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