Nervous Regulation of Biliary Tract Motility
Puzikov, A.M.; Lychkova, A.E.
Eksperimental'naia i Klinicheskaia Gastroenterologiia 7: 62-65
2016
ISSN/ISBN: 1682-8658 PMID: 30284425 Document Number: 688857
The study of mechanisms of regulation of biliary tract motility by divisions of autonomic nervous system (ANS). Experiments were carried out on rabbits, chinchillas weighing 3.5-4 kg using gentle methods of treatment of experimental animals. Electromotor activity of electromotor (EMA) of the gallbladder and sphincter of Oddi was recorded. Irritation of the nerve produces an electrical pulse duration of 2 ms, the amplitude of 1.5-15 V, frequency of 10 Hz. The mechanism of vagal inhibition of sphincter of Oddi motility and unidirectional stimulatory influence of ANS divisions on the motility of the gallbladder and sphincter of Oddi was studied. It was established that in the mechanism of vagal inhibition of sphincter of Oddi motility involved intramural adrenergic neurons synaptically connected with preganglionic parasympathetic fibers. At the stimulatory effect of vagus on biliary tract motility serotonergic intramural neurons are involved transmitting excitation to serotonin receptors of effector tissue.