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Chemical constituents and cytotoxicity assay research in small polar substances from Vitis thunbergii var. taiwaniana

Jiang, C.; Wang, W.-z.; Liao, X.-j.; Zeng, D.-q.; Ling, T.; Xu, S.-l.; Zeng, J.-z.; Chen, H.-f.

Zhongguo Zhong Yao Za Zhi 40(15): 2999-3004

2015

ISSN/ISBN: 1001-5302
PMID: 26677700
Document Number: 682338
This article studied the chemical constituents from the aerial part of Vitis thunbergii var. taiwaniana. The 60% ethanol extract was eluted with 95% ethanol though HP-20 macroporous adsorption resin column. 12 compounds, including (1) betulinic acid, (2)2, 2, 2'-bis (4-hydroxyphenyl) propane bis (2, 3-epoxypropyl) ether, (3) eriodictyol, (4) trans-ε-viniferin, (5) (+)-cis-ε-viniferin, (6) kobophenol A, (7) ampelopsin A, (8) nepalensinol B, (9) cis-miyabenol C, (10) cis-vitisin B, (11) cis-gnetin H and (12) (+)-hopeaphenol, were separated by using normal phase silica gel, ODS, Sephdadex LH-20 column chromatographies and semi-preparative or preparative HPLC. Compounds 2, 5, 6, 8, 9, 10, 11 were separated from the genus Vitis for the first time and compounds 3, 7, 12 were separated from Vitis thunbergii var. taiwaniana for the first time. At a concentration of 50 μmol · L(-1), compound 6, 7 and 11 showed strong cytotoxicity against MCF-7 cell lines with the inhibition rate of 66.58%, 57.16%, 52.84%, respectively.

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Zhang, J.X.; Ma, G.E.; Lao, A.N.; Xu, R.S. 1991: Studies on chemical constituents of Fritillaria thunbergii Miq Yao Xue Xue Bao 26(3): 231-233
Shang, X.-Y.; Liu, W.; Zhao, C.-W. 2008: Advances in research of chemical constituents and pharmacological activites of Bauhinia Zhongguo Zhong Yao Za Zhi 33(6): 709-717
Li, S.-p.; Sha, L.; Zhao, Y.-w.; Xu, Z.-l.; Huang, W.-z.; Wang, Z.-z.; Xiao, W. 2015: Advance in research on chemical constituents from Notopterygii Rhizoma et Radix Zhongguo Zhong Yao Za Zhi 40(15): 2952-2963
Sun, C.-n.; Zhu, Y.; Xu, X.-m.; Yu, J.-n. 2014: Advances in research of chemical constituents and pharmacological activities of common used spices Zhongguo Zhong Yao Za Zhi 39(21): 4153-4158
Gao, W.; Li, Z.; Xiao, P. 1997: Peroxidase assay over the course of dormancy relieving with low temperature in Fritillaria thunbergii Miq. by electrophoresis Zhongguo Zhong Yao Za Zhi 22(9): 530
Chandra, S.; Lorey, D.R. 2001: SIMS ion microscopy in cancer research: single cell isotopic imaging for chemical composition, cytotoxicity and cell cycle recognition Cellular and Molecular Biology 47(3): 503-518
Yeung, D.T.; Harper, J.R.; Platoff, G.E. 2020: Supporting Fundamental Chemical Toxicology Research To Inform Medical Countermeasure Developments: The National Institutes of Health Chemical Countermeasures Research Program Chemical Research in Toxicology 33(4): 855-859
Golli, V.; Berilă, I.; Diaconu, S.; Ionescu, N.; Corîciu, S.; Stefănescu, I.; Stefanin, E.; Gherman, V.; Beano, M. 1982: Research on the occurrence of functional anomalies of the peripheral bronchi (small bronchi disease) in workers in a factory with respiratory noxious substances Revista de Igiena Bacteriologie Virusologie Parazitologie Epidemiologie Pneumoftiziologie. Pneumoftiziologia 31(2): 117-128
Bradley, T.P.; Bonavida, B. 1982: Mechanism of cell-mediated cytotoxicity at the single cell level. IV. Natural killing and antibody-dependent cellular cytotoxicity can be mediated by the same human effector cell as determined by the two-target conjugate assay Journal of Immunology 129(5): 2260-2265
Johnson, T. 1995: Chemical synthesis of polar zipper peptides: motifs for potential protein association in inherited neurodegenerative diseases Biomedical Peptides Proteins and Nucleic Acids: Structure Synthesis and Biological Activity 1(4): 247-249
Pil'ganchuk, V.V. 1979: Polar compiplanimetry, a new method for the quantitative evaluation of campimetric research data Vestnik Oftalmologii 3: 59-63
Qiao, D.; Gan, L.-S.; Mo, J.-X.; Zhou, C.-X. 2012: Chemical constituents of Acorus calamus Zhongguo Zhong Yao Za Zhi 37(22): 3430-3433
Zeng, X.; Fang, Z.; Ma, J. 1991: Chemical constituents of Osbeckia chinensis L Zhongguo Zhong Yao Za Zhi 16(2): 99
Zhou, Y.H.; Zou, H.J. 1993: Studies on chemical constituents of naringin Zhongguo Zhong Yao Za Zhi 18(12): 737-738; 763
Tao, J.; Fang, W. 2012: Chemical constituents from Sambucus chinensis Zhongguo Zhong Yao Za Zhi 37(10): 1399-1401
Wang, G.; Wang, G.; Lin, B.; Bai, Y.; Qin, M. 2012: Chemical constituents from Gueldenstaedtia stenophylla Zhongguo Zhong Yao Za Zhi 37(10): 1412-1416
Tan, C.-y.; Wang, J.-h.; Li, X.; Du, Y.-g.; Bai, X.-f. 2003: Chemical constituents of Cyanotis arachnoidea Yao Xue Xue Bao 38(10): 760-762
Ma, J.; Yang, J.; Ji, T.; Wang, A.; Su, Y. 2012: Chemical constituents from Hypericum perforatum Zhongguo Zhong Yao Za Zhi 37(16): 2408-2412
Li, C.; Gou, Z.; Yang, Y.; Zhang, C. 1999: Chemical constituents of Cynanchum chinense R. Br Zhongguo Zhong Yao Za Zhi 24(6): 353-355; 383
Wang, L.; Yu, M.-M.; Chi, Y.-Q.; Ouyang, W.-B.; Zang, Z.; Zhao, Y. 2014: Chemical constituents of Euphorbia dracunculoides Zhongguo Zhong Yao Za Zhi 39(20): 3969-3973