Effects of omega-3 polyunsaturated fatty acids on the state of insulin resistance, the content of some pro- and antiinflammatory factors in patients with type 2 diabetes mellitus and cardiovascular autonomic neuropathy
Serhiyenko, V.A.
Voprosy Pitaniia 84(6): 76-82
2015
ISSN/ISBN: 0042-8833 PMID: 29378101 Document Number: 681778
We have investigated the influence of the long-chain ω-3 polyunsaturated fatty acids (ω-3 PUFA) administration on the insulin resistance parameters, levels of high sensitivity C-reactive protein (hsCRP), some pro- and anti-inflammatory cytokines in patients with type 2 diabetes mellitus (T2 DM) and cardiovascular autonomic neuropathy (CAN). The study involved 12 patients with T2 DM without verified cardiovascular diseases (CVD), 36 patients with T2 DM and functional stage of CAN, of median age 50–59 years, disease duration 1–6 years and HbA1c levels – 7.1±0.6%. 15 healthy subjects were control group. Screening for CAN, that included five standard cardiovascular tests, was performed.