Recent advances in medical and surgical treatment of ulcerative colitis
Sugita, A.; Koganei, K.; Tatsumi, K.; Futatsuki, R.; Kuroki, H.; Yamada, K.; Arai, K.; Fukushima, T.
Nihon Geka Gakkai Zasshi 116(2): 99-103
2015
ISSN/ISBN: 0301-4894 PMID: 26050509 Document Number: 680588
Recent advances in both medical and surgical treatment of ulcerative colitis have been remarkable. Changes in medical treatment are mainly good results of therapy with the anti-TNF-α antibody, tacrolimus, and those in surgical treatment are an expansion of the surgical indications to include patients with intractable disease, such as treatment refractoriness and chronic corticosteroid dependence, by a better postoperative clinical course after pouch surgery, improred selection of surgical procedures and the timing of surgery in elderly patients. To offer the optimal treatment for patients with ulcerative colitis, new medical therapies should be analyzed from the standpoint of the efficacy and limitations of effect. Long postoperative clinical course of surgical patients including colitic cancer, prevention of postoperative complications should be also analyzed.