Surgical treatment of ulcerative colitis and familial adenomatous polyposis: recent developments
Van Laarhoven, C.J.; Schipper, M.E.; van Vroonhoven, T.J.; Gooszen, H.G.
Nederlands Tijdschrift Voor Geneeskunde 143(13): 662-666
1999
ISSN/ISBN: 0028-2162 PMID: 10321297 Document Number: 500315
Reconstructive surgery for ulcerative colitis and familial adenomatous polyposis nowadays usually takes the form of an ileoanal pouch, involving making a reservoir of the terminal portion of the ileum which subsequently is anastomosed to the anal canal. This method results in definite cure in many cases, but is associated with a morbidity of 15-30% and fails in 10%. A new surgical treatment includes complete removal of the affected large bowel mucosa, guaranteeing oroanal intestinal continuity, limiting complications and providing good function of the reservoir or of the new rectum. In creation of an ileoneorectal anastomosis, complete removal of the affected mucous membrane is followed by preparing a functional 'neorectum' by means of pedicle grafting of ileal mucous membrane on to the uncovered muscular wall of the rectum. This operation gave good results in a small-scale clinical trial.