Diagnosis and medical treatment of pouchitis in ileal pouch-anal anastomosis in patients with ulcerative colitis
Okazaki, K.; Matsushita, M.; Kawamata, S.; Shimatani, M.; Fujii, T.
Nihon Rinsho. Japanese Journal of Clinical Medicine 63(5): 885-889
2005
ISSN/ISBN: 0047-1852 PMID: 15881186 Document Number: 586562
Pouchitis is a common and long-term complication of ileal pouch-anal anastomosis in patients with underlying ulcerative colitis. Combination with clinical symptoms, endoscopic and histopathological findings are required to make accurate diagnosis. Ciprofloxacin and metronidazole are effective in patients with acute pouchitis. Probiotics may be useful in maintaining regression and preventing from remission. Immunomodulating agents are also useful in chronic pouchitis.