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Permeation study through bacterial cellulose membrane

Wu, C.; Murtaza, G.; Yameen, M.A.; Aamir, M.N.; Akhtar, M.; Zhao, Y.

Acta Poloniae Pharmaceutica 71(2): 297-300

2014

ISSN/ISBN: 0001-6837
PMID: 25272650
Document Number: 677672
Abstract: The objective of this study was to fabricate topical formulations of diclofenac diethylamine (DD) using isopropyl myristate (IPM) and isopropyl palmitate (IPP) as permeation enhancers. Franz cell and bacterial cellulose were used as analytical instrument and diffusion membrane, respectively. Permeation enhancers exhibited significant effect on the permeation characteristics of DD. It was concluded from the results that improved permeation of DD was observed when IPP was used as enhancer.

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