Raltegravir. In HIV-infected in children at least 2 years of age. Only after prior treatment failure
Prescrire International 23(152): 206
2014
ISSN/ISBN: 1167-7422 PMID: 25325117 Document Number: 677336
The first integrase inhibitor to be approved for children; antiretroviral effect similar to that observed in adults in treatment failure; no first-line evaluation.
Document emailed within 1 workday
Related Documents
Penda, C.I.; Bebey, F.S.; Mangamba, D.K.; Moukoko, E.C.E.; Ngwa, V.; Makouet, N.; Bissek, A.-C.éc.; Minkemdefo, B.D.; Tetanye, E.; Ndombo, P.K. 2013: Treatment failure in children infected with HIV in routine follow-up in a resource-limited setting in Cameroon Pan African Medical Journal 15: 80Siegfried, N.; Davies, M-Ann.; Penazzato, M.; Muhe, L.M.; Egger, M. 2013: Optimal time for initiating antiretroviral therapy (ART) in HIV-infected, treatment-naive children aged 2 to 5 years old Cochrane Database of Systematic Reviews 2013(10): Cd010309
Sutcliffe, C.G.; Scott, S.; Mugala, N.; Ndhlovu, Z.; Monze, M.; Quinn, T.C.; Cousens, S.; Griffin, D.E.; Moss, W.J. 2008: Survival from 9 months of age among HIV-infected and uninfected Zambian children prior to the availability of antiretroviral therapy Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America 47(6): 837-844
Bacha, T.; Tilahun, B.; Worku, A. 2012: Predictors of treatment failure and time to detection and switching in HIV-infected Ethiopian children receiving first line anti-retroviral therapy Bmc Infectious Diseases 12: 197
Westley, B.P.; DeLong, A.K.; Tray, C.S.; Sophearin, D.; Dufort, E.M.; Nerrienet, E.; Schreier, L.; Harwell, J.I.; Kantor, R. 2012: Prediction of treatment failure using 2010 World Health Organization Guidelines is associated with high misclassification rates and drug resistance among HIV-infected Cambodian children Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America 55(3): 432-440
Chhagan, M.K.; Kauchali, S.; Arpadi, S.M.; Craib, M.H.; Bah, F.; Stein, Z.; Davidson, L.L. 2011: Failure to test children of HIV-infected mothers in South Africa: implications for HIV testing strategies for preschool children Tropical Medicine and International Health: Tm and Ih 16(12): 1490-1494
Andersen, G.E.; Hejl, M.; Christensen, N.C.; Bott-Petersen, H.; Lous, P.; Friis-Hansen, B. 1982: Occurrence of hyperlipemia in 1 407 Danish children and young adults whose fathers had died from ischemic heart disease prior to the age of 45 years Ugeskrift for Laeger 144(13): 926-930
Mgelea, E.M.; Kisenge, R.; Aboud, S. 2014: Detecting virological failure in HIV-infected Tanzanian children South African Medical Journal 104(10): 696-699
Ulstein, M.; Jensen, T.S.; Irgens, L.M.; Lie, R.T.; Sivertsen, E. 1990: Outcome of pregnancy in one Norwegian county 3 years prior to and 3 years subsequent to the Chernobyl accident Acta Obstetricia et Gynecologica Scandinavica 69(4): 277-280
Shet, A.; Mehta, S.; Rajagopalan, N.; Dinakar, C.; Ramesh, E.; Samuel, N.M.; Indumathi, C.K.; Fawzi, W.W.; Kurpad, A.V. 2009: Anemia and growth failure among HIV-infected children in India: a retrospective analysis Bmc Pediatrics 9: 37
Styczyński, J.; Smukalska, E.; Dorau, M. 1995: Evolution of viral hepatitis B markers in children infected with HBV in the first two years of life Pediatria Polska 70(5): 389-394
Penazzato, M.; Prendergast, A.J.; Muhe, L.M.; Tindyebwa, D.; Abrams, E.J. 2014: Optimization of antiretroviral therapy in HIV-infected children under 3 years of age: a systematic review Aids 28 Suppl. 2: S137-S146
Bazin, G.Ricordi.; Gaspar, M.Curto.Saavedra.; Silva, N.Carvalho.Xavier.Micheloni.da.; Mendes, C.da.Costa.; Oliveira, C.Pichler.de.; Bastos, L.Soares.; Cardoso, C.Aparecida.Araújo. 2014: Antiretroviral therapy in HIV-infected children and adolescents: lessons learned in 30 years of the epidemic Cadernos de saude publica 30(4): 687-702
Beetke, E.; Brepohl, S.B.; Wagner, K.D. 1991: Modification of anxiety in children prior to dental treatment using premedication with Faustan diazepam) Kinderarztliche Praxis 59(11): 336-340
Walters, E.; Duvenhage, J.; Draper, H.R.; Hesseling, A.C.; Van Wyk, S.S.; Cotton, M.F.; Rabie, H. 2014: Severe manifestations of extrapulmonary tuberculosis in HIV-infected children initiating antiretroviral therapy before 2 years of age Archives of disease in childhood 99(11): 998-1003
Shiri, T.; Auranen, K.; Nunes, M.C.; Adrian, P.V.; van Niekerk, N.; de Gouveia, L.; von Gottberg, A.; Klugman, K.P.; Madhi, S.A. 2013: Dynamics of pneumococcal transmission in vaccine-naive children and their HIV-infected or HIV-uninfected mothers during the first 2 years of life American journal of epidemiology 178(11): 1629-1637
Ndeezi, G.; Tumwine, J.K.; Bolann, Børn.J.; Ndugwa, C.M.; Tylleskär, T. 2010: Zinc status in HIV infected Ugandan children aged 1-5 years: a cross sectional baseline survey Bmc Pediatrics 10: 68
Chalamilla, G.; Hawkins, C.; Okuma, J.; Spiegelman, D.; Aveika, A.; Christian, B.; Koda, H.; Kaaya, S.; Mtasiwa, D.; Fawzi, W. 2012: Mortality and treatment failure among HIV-infected adults in Dar Es Salaam, Tanzania Journal of the International Association of Physicians in Aids Care 11(5): 296-304
Vanprapar, N.; Chearsakul, S.; Chokephaibulkit, K.; Phongsamart, W.; Lolekha, R. 2002: High CD4+ T-cells percentage and/or low viral load are predictors of 1-5 years survival in HIV-1 vertically infected Thai children Journal of the Medical Association of Thailand 85(Suppl): S690-S693
Aurpibul, L.; Puthanakit, T.; Taecharoenkul, S.; Sirisanthana, T.; Sirisanthana, V. 2009: Reversal of growth failure in HIV-infected Thai children treated with non-nucleoside reverse transcriptase inhibitor-based antiretroviral therapy Aids Patient Care and Stds 23(12): 1067-1071