Evolution of viral hepatitis B markers in children infected with HBV in the first two years of life
Styczyński, J.; Smukalska, E.; Dorau, M.
Pediatria Polska 70(5): 389-394
1995
ISSN/ISBN: 0031-3939 PMID: 8692592 Document Number: 454132
Circumstances of acquiring an infection, spontaneous evolution of markers during 6 years of follow-up, laboratory findings and results of liver biopsies were analysed in 51 children infected with HBV during the first two years of life; 76.5% of them developed chronic carrier state. ALAT values were periodically increased in 34 children (66.6%) and elimination of HBeAg i HBsAg occurred in 17 (33.3%) and 12 children (23.5%), respectively, during the first year of follow-up. Seroconversion was observed only in a few cases in the subsequent years. Anti-HBc IgM antibodies were detectable for a mean period of less than 7 months (p < 0.02) after diagnosis of infection.