Research about effect of spray drying conditions on hygroscopicity of spray dry powder of gubi compound's water extract and its mechanism
Zong, J.; Shao, Q.; Zhang, H.-Q.; Pan, Y.-L.; Zhu, H.-X.; Guo, L.-W.
Zhongguo Zhong Yao Za Zhi 39(4): 663-668
2014
ISSN/ISBN: 1001-5302 PMID: 25204143 Document Number: 676928
To investigate moisture content and hygroscopicity of spray dry powder of Gubi compound's water extract obtained at different spray drying conditions and laying a foundation for spray drying process of Chinese herbal compound preparation. In the paper, on the basis of single-factor experiments, the author choose inlet temperature, liquid density, feed rate, air flow rate as investigated factors. The experimental absorption rate-time curve and scanning electron microscopy results showed that under different spray drying conditions the spray-dried powders have different morphology and different adsorption process. At different spray-dried conditions, the morphology and water content of the powder is different, these differences lead to differences in the adsorption process, at the appropriate inlet temperature and feed rate with a higher sample density and lower air flow rate, in the experimental system the optimum conditions is inlet temperature of 150 degrees C, feed density of 1.05 g x mL(-1), feed rate of 20 mL x min(-1) air flow rate of 30 m3 x h(-1).