Effect of inhalation of insecticide spray on learning and memory in rats
Mathew, R.; Verghese, J.; Venkataraman, B.V.; Joseph, T.
Indian Journal of Experimental Biology 27(3): 258-260
1989
ISSN/ISBN: 0019-5189 PMID: 2606533 Document Number: 648
Acute exposure to insecticide (Baygon-spray; 5 ml/animal/5 min) inhalation in rats did not affect the learning process but produced a significant loss of memory (P less than 0.01 less than 0.001) whereas chronic exposure (one exposure per day for three weeks) produced a significant delay in learning (P less than 0.05) and memory (P less than 0.01). Acetylcholinesterase activity in brain after acute and chronic exposure declined significantly (P less than 0.01) during the learning process but returned to normal after 24 hr.
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