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Two cases of complete response for cStage I ( T1bN0M0) esophageal carcinoma treated with chemoradiation therapy

Nishigaki, T.; Okada, K.; Ebisui, C.; Wada, Y.; Kato, R.; Makino, S.; Owada, Y.; Murakami, M.; Yanagisawa, T.; Okamura, S.; Murata, K.; Yokouchi, H.; Kinuta, M.

Gan to Kagaku Ryoho. Cancer and ChemoTherapy 39(12): 2107-2109

2012

ISSN/ISBN: 0385-0684
PMID: 23267992
Document Number: 663117
We report 2 cases of complete response for cStage I(T1bN0M0) esophageal carcinoma treated with chemoradiation therapy. Case 1: A 70-year-old man was diagnosed with cStage I(T1bN0M0) thoracic esophageal carcinoma(Type 0- IIc, squamous cell carcinoma). efinitive chemoradiotherapy (5-FU 250 mg/m2, CDDP 5 mg/m2 days 1-5, 8-12, 15-19, 22-26, 29-33, and 36-40; radiation: 60 Gy/30 Fr) was administrated. After treatment, we confirmed that the esophageal lesion had disappeared by upper endoscopy. Case 2: A 78-year-old man was diagnosed with cStage I(T1bN0M0) thoracic esophageal carcinoma (Type 0-I+IIb, squamous cell carcinoma) and early stage gastric carcinoma. Considering his general condition, radical surgery for esophageal cancer and gastric cancer was difficult; hence, he was treated with definitive chemoradiotherapy. After treatment, the esophageal lesion disappeared and we performed fundusectomy. Chemoradiation therapy appears to be effective for patients with cStage I(T1bN0M0) esophageal carcinoma.

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