A case successfully treated with abdominoperineal resection after preoperative chemoradiation therapy for anal cancer
Honboh, T.; Kudo, K.; Ninomiya, M.; Hamatsu, T.; Hasegawa, H.; Kabashima, A.; Ushijima, C.; Kitamura, M.
Gan to Kagaku Ryoho. Cancer and ChemoTherapy 38(12): 2283-2285
2011
ISSN/ISBN: 0385-0684 PMID: 22202356 Document Number: 652909
A 46-year-old female was diagnosed with anal squamous cell carcinoma. Chemoradiation therapy was administered for a first-line therapy. Two courses of enforced 5-FU/MMC combination therapy were administered along with radiotherapy (60 Gy). This chemoradiation therapy had complete response. However, three months after, anal cancer had a local recurrence. Since there was no distant metastasis, abdoninoperineal resection was performed. No complications were observed after the operation. We conclude that abdominoperineal resection may be effective in the treatment of anal cancer in cases which the local recurrence was observed after chemoradiation therapy.