Risk of gastric cancer dependent on serological markers of atrophic gastritis: cohort study
Reshetnikov, O.V.; Openko, T.G.; Simonova, G.I.; Kurilovich, S.A.; Maliushina, S.K.; Ragino, I.I.; Voevoda, M.I.
Voprosy Onkologii 58(5): 644-648
2012
ISSN/ISBN: 0507-3758 PMID: 23600281 Document Number: 659893
In a prospective study the risk of subsequent gastric cancer (GC) was assessed in persons aged 45-69 over 5 years after the initial testing with a set of serological tests (pepsinogen I, pepsinogen II, gastrin-17, antibodies to Helicobacter pylori). The presence of gastric atrophy markers was a significant predictor of GC in the forthcoming years. Non-invasive techniques may be used in the formation of high-risk groups, followed by GC active surveillance.