Application of coenzyme Q (10) in combination therapy of arterial hypertension
Mikhin, V.P.; Kharchenko, A.V.; Rosliakova, E.A.; Cherniatina, M.A.
Kardiologiia 51(6): 26-31
2011
ISSN/ISBN: 0022-9040 PMID: 21878067 Document Number: 650986
We studied effect of coenzyme Q(10) on 24-hour blood pressure profile and function of vascular endothelium in patients with essential hypertension. Coenzyme Q(10) was used as a component of combination therapy comprising angiotensin converting enzyme inhibitor enalapril. Administration of coenzyme Q(10) in combination with traditional antihypertensive therapy promoted normalization of vascular endothelial function and more effective correction of 24-hour blood pressure profile. These findings allow to consider the use of coenzyme Q(10) as promising component of combination therapy of arterial hypertension.