Thromboprophylaxis in pregnant women should be individually tailored
Spaanderman, M.A.C.
Nederlands Tijdschrift Voor Geneeskunde 155(18): A3568
2011
ISSN/ISBN: 1876-8784 PMID: 21557830 Document Number: 650230
Roeters van Lennep et al. recently evaluated efficacy and safety of thromboprophylaxis with low dose low-molecular-weight heparin (LMWH) in women with intermediate and high risk of pregnancy-related venous thromboembolism (VTE). Lessons to be drawn from this study are that the risk of VTE should be estimated preconceptionally, that the current LMWH prophylaxis is sufficient during pregnancy and the post-partum period for women with an intermediate risk of VTE, that from a haemostatic point of view the post-partum period does not end at 6 weeks but at 3 months, and that the prophylactic LMWH dosage is insufficient in 1 out of 20 women with a high risk of VTE.