Treatment of severe chromoblastomycosis with itraconazole and 5-flucytosine association
Antonello, V.Sperb.; Appel da Silva, M.Campos.; Cambruzzi, E.; Kliemann, D.Alexandre.; Santos, B.Riegel.; Queiroz-Telles, Fávio.
Revista do Instituto de Medicina Tropical de Sao Paulo 52(6): 329-331
2010
ISSN/ISBN: 0036-4665 PMID: 21225217 Document Number: 647244
Chromoblastomycosis is a chronic human melanized fungi infection of the subcutaneous tissue caused by traumatic inoculation of a specific group of dematiaceous fungi through the skin, often found in barefooted agricultural workers, in tropical and subtropical climate countries. We report the case of a male patient presenting a slow-growing pruriginous lesion on the limbs for 20 years, mistreated over that time, which was diagnosed and successfully treated as chromoblastomycosis. Besides the prevalence of this disease, treatment is still a clinical challenge.