Itraconazole in the treatment of Candida vulvovaginitis in patients with type Ii diabetes mellitus (non-insulin dependent)
González Ortiz, M.; Martínez Abundis, E.
Ginecologia y Obstetricia de Mexico 63: 15-18
1995
ISSN/ISBN: 0300-9041 PMID: 7896149 Document Number: 440342
The purpose of this study was to know the utility of traditional administration of itraconazole to vulvovaginitis by Candida in patients with diabetes mellitus. A randomized, single blind, controlled clinical assay, was carried out in 32 patients with diabetes mellitus type II and vulvovaginitis for Candida albicans. A study group was formed with 16 patients. They received 200 mg/day of itraconazole with breakfast for 3 days. The other 16 women were the control group. A good clinical response was obtained in 87.50% of the patients (p = 0.001). Candida disappeared in 56.25% of the cases. General response showed medication failure in 43.75%. It is concluded that the traditional treatment of itraconazole for vulvovaginitis for Candida albicans in women with diabetes mellitus is a good choice to control the signs and symptoms, but it doesn't erradicate the fungus.