Research on chromatographic fingerprint of fruits of Schisandra chinesis
Wang, W.; Ye, Z.; Song, L.; Shen, W.; Guo, Q.; Li, D.; Zhou, D.
Zhongguo Zhong Yao Za Zhi 35(21): 2871-2873
2010
ISSN/ISBN: 1001-5302 PMID: 21322949 Document Number: 647171
To study the chromatographic fingerprint of the fruits of Schisandra chinensis, and identify the peaks. Analysis was performed at 30 degrees C on a Waters Symmetry C18 column (4.6 mm x 250 mm, 5 microm), eluted with acetonitrile-water gradient elution. The flow-rate was 1.0 mL x min(-1), and detection wavelength was 218 nm. The peaks in the chromatogram were identified by LC-MS. The fingerprint of the fruits of S. chinensis was established, and fifteen peaks of lignans were identified. The method was easy, reliable and could be used as a powerful tool for the further quality control of S. chinensis.