The study of the sensitive and specificity on HBV DNA replication by HBV-lP detecting
Shan, P.-N.; Lu, Z.-Y.; Xuan, G.-H.; Weng, L.-M.; Ru, J.-C.; Tan, S.-H.; Xu, D.-S.
Zhonghua Shi Yan he Lin Chuang Bing du Xue Za Zhi 24(1): 68-70
2010
ISSN/ISBN: 1003-9279 PMID: 20848857 Document Number: 638753
To detect HBV-LP and HBV DNA of the patients with hepatitis B, and to study the sensitive and specificity of HBV-LP detecting and its evaluate on for clinical application. The ELISA was used for HBV-LP detecting and RT-PCR for HBV DNA detecting. The sensitive and specificity of HBV-LP and HBV DNA were 64.89%, 99.68%, 60.63% and 100% respectively (P > 0.05); +LR, -LR were 202.78, 60.63, 0.3522 and 0.3937, and there were significance between +LR of the detecting (P < 0.005). The sensitive and specificity of HBV-LP and HBV DNA detecting are considerable, +LR of HBV-LP are higher comparing HBV DNA. The HBV-LP is better serology index for detecting replication of HBV DNA.