Use of a highly-sensitive method of electrophoresis-precipitation for detecting hepatitis B virus antigen in human serum
Grannikova, S.A.; Budnitskaia, P.Z.
Biulleten' Eksperimental'noi Biologii i Meditsiny 83(4): 508-509
1977
ISSN/ISBN: 0365-9615 PMID: 403983 Document Number: 115833
A modification of the highly-sensitive method of electrophoresis-precipitation in polyacrylamide gel used for detection of the virus hepatitis B antigen (HBsAg) and the anti-HBsAg is described. The method completely retains the specificity of the gel immunodiffusion test, but is 100--2000 times more sensitive in HBsAg detection. The sera of patients with different pathology were checked by this method. In comparison with the methods used before the HBsAg determination by the mentioned method proved to be more effective.