The process of remodeling of left chambers of the heart and dysfunction of endothelium of peripheral vessels in hypertensive premenopausal women
Khabibulina, M.M.; Serebrennikov, R.V.; Iordanidi, I.S.; Grishina, I.F.
Kardiologiia 49(2): 47-51
2009
ISSN/ISBN: 0022-9040 PMID: 19254216 Document Number: 637278
Results of ultrasound study of 230 premenopausal women with I-II stage essential hypertension (EH) in relation to functional state of endothelium of peripheral arteries are presented. Endothelial dysfunction in hypertensive premenopausal women can be one of factors contributing to remodeling of left cardiac chamber. Women with EH and endothelial dysfunction compared with those with conserved vascular endothelial function more often had hypertrophic variants of left ventricular myocardial remodeling (mostly of concentric type). Premenopausal women with EH had diastolic dysfunction of the left ventricle with impairment of both its rigidity and active relaxation, more pronounced in the presence of dysfunction of endothelium of peripheral vessels.