Chronic eosinophilic leukemia with a unique translocation
Arora, R.S.
Indian Pediatrics 46(6): 525-527
2009
ISSN/ISBN: 0019-6061 PMID: 19556663 Document Number: 633496
We report a case of chronic eosinophilic leukemia in a 9 year old girl who presented with anemia, thrombocytopenia, leucocytosis (mostly dysplastic eosinophils), lymphadenopathy and hepatosplenomegaly. There was no increase in blasts but myelofibrosis was seen in the bone marrow. A previously unreported translocation 46,XX,t(1;4)(q24;q35), was found on cytogenetic analysis and involvement of the myocardium was also present. Shortly after commencing steroids, the family abandoned therapy.
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