Influence of honey, royal jelly and propolis on accelerating acetate healing of experimental gastric ulcers in rats
Belostotskiĭ, N.I.; Kas'ianenko, V.I.; Dubtsova, E.A.; Lazebnik, L.B.
Eksperimental'naia i Klinicheskaia Gastroenterologiia 6: 46-50
2009
ISSN/ISBN: 1682-8658 PMID: 20201286 Document Number: 628966
This study examines gastric acetic ulcer healing in the rat after administration of honey, royal jelly and propolis into the stomach. Chronic gastric ulcers were induced in male Wistar rats by the application of 100% acetic acid to the serosal surface of the stomach on 60 sec. Bee-keeping products were administrated into the stomach from 2nd to 7th day after acetic ulcer induction. On 7th day animals were killed, and ulcer area was measured in mm2. In gastric juice pH and activity of pepsin were measured. The healing of acetic ulcers is accelerated with the administration of honey, royal jelly or propolis during six days. The largest healing effect was demonstrated with propolis and royal jelly, smaller one with the honey. It was revealed decrease of stomach acid secretion in the rats, which have received bee-keeping products versus the rats of control group.