Biosynthesis of macrocyclic trichothecenes: some aspects of physiology
Zaĭchenko, O.M.
Mikrobiolohichnyi Zhurnal 70(2-3): 116-121
2008
ISSN/ISBN: 0201-8462 PMID: 18663931 Document Number: 626624
The data of long-term investigations of the control of macrocyclic trichothecenes biosynthesis by means ofthe elements of mineral nutrition, microelements in particular in Dendrodochium toxicum Pidopl. et Bilai are presented. The media for providing the dominant synthesis (50-70 %) of certain component from the composite complex of dendrodochins and so for obtaining the fractions enriched with this component, have been worked out. This method simplifies considerably the isolation of components in the crystal state. The media for obtaining verrucarin A, roridin A and roridin H are proposed.