The glomerular apparatus and renal blood flow in rats during postnatal ontogenesis

Shyyrapaĭ, U.V.; Belichenko, V.M.; Shoshenko, K.A.; Aĭzman, R.I.

Rossiiskii Fiziologicheskii Zhurnal Imeni I.M. Sechenova 94(4): 456-464

2008


ISSN/ISBN: 0869-8139
PMID: 18666640
Document Number: 620374
In anesthetized Wistar rats of the age of 4, 12, 30 and 65 days, the renal blood flow (RBF) with laser-Doppler flowmetry, diameter, number and density of glomeruli, diameter of afferent and efferent arterioles were measured. We found that during rat development the RBF increased 2.8-fold, the diameter of glomeruli--3.6-fold, diameter of afferent arterioles--1.8-fold, and the efferent arterioles--rose 1.3-fold. The number of glomeruli increased 1.3-fold, but their density decreased 16-fold.

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